Menopausal Dyspareunia and Probiotics: A Future Approach?
Neu, Ellen L.
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Session presented on Saturday, July 25, 2015: Purpose: A pilot study was conducted for the inquiry of vaginal probiotics for menopausal women with self-reported dyspareunia. Methods: Initial menopausal survey tool for assessment of urinary incontinence, dyspareunia and general vasomotor complaints allowed for women with self-reported dyspareunia to be further evaluated. potential candidates where then contacted and offered the opportunity to participate in an open lable study using a vaginal probiotic once per week for 6 weeks. After full disclosure and IRB approved consent was signed, the subjects examined and vaginal ph measurement obtained. The Female Sexual Function Index (FSFI, 2002) was administered. After 6 weeks of intervention, the women returned, repeated the FSFI and were examined with vaginal ph reassesed. A diary of dates and times probiotic was used and sexual intercourse took place was kept during the study and turned in to the PI. Results: 107 menopausal women were screened, 37 fit the criteria of self-reported dyspareunia. 10 entered the enrollment process, only 7 completed. 2 discontinued the study due to out of state travel and 1 due to partners sudden illness. FSFI scores showed improvements in all 6 domains, including a decrease in pain and vaginal dryness. Conclusion: The initial data suggests larger enrollment and data collection will be necessary. Further research into the vaginal microbiome and its role in vaginal function is needed.